A dish that promises indulgence in every single bite, this Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta brings bold flavors and creamy comfort to your table. Imagine tender rotini pasta coated in a silky cheese sauce, spiked with a gentle Cajun heat, and topped with a savory ground beef mixture that melts seamlessly into the Alfredo Velveeta blend.
This pasta is the ultimate crowd-pleaser, perfect for busy weeknights, casual get-togethers, or cozy family dinners. It’s the kind of meal that instantly draws everyone to the kitchen with its aroma of garlic, buttery cheese, and spiced beef.
What Makes This Pasta Special?
The twist in this pasta comes from the combination of Cajun seasoning and Alfredo Velveeta cheese. The Cajun spice gives it a warm kick without overpowering the rich creaminess of the cheese, while the twisted pasta holds onto every bit of the luscious sauce. This marriage of flavors transforms a simple beef and pasta dinner into a restaurant-worthy comfort meal.


Ingredients for Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta
- Rotini Pasta (Twisted Pasta): The spiral shape traps the creamy cheese sauce for a perfect bite.
- Ground Beef: Savory and hearty, creating the base of the sauce.
- Velveeta Cheese: Essential for that melty, smooth, and ultra-creamy texture.
- Alfredo Sauce: Adds richness and depth, pairing perfectly with Cajun spice.
- Garlic (minced or powder): Infuses warmth and aromatic flavor throughout the dish.
- Cajun Seasoning: Brings a smoky, zesty kick that elevates the beef and cheese.
- Shredded Mozzarella or Parmesan (optional for topping): Melts beautifully for a gooey finish.
- Fresh Parsley (optional): Adds a pop of color and freshness before serving.
How To Make Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta
Step 1: Boil the Pasta
Bring a large pot of salted water to a boil and cook the rotini pasta according to package instructions until al dente. Drain, toss with a little butter or olive oil, and set aside.
Step 2: Cook the Cajun Ground Beef
In a large skillet, brown the ground beef over medium heat. Drain any excess grease, then season with Cajun seasoning and minced garlic. Stir well until the beef is fragrant and coated in spices.
Step 3: Prepare the Creamy Cheese Sauce
Reduce the heat to low and add the Alfredo sauce and cubed Velveeta cheese to the skillet. Stir continuously until the cheese melts into the sauce, forming a smooth and creamy mixture.
Step 4: Combine Pasta and Sauce
Add the cooked rotini pasta into the skillet with the cheesy beef mixture. Gently toss until every twist of pasta is coated in the creamy Cajun Alfredo sauce.
Step 5: Optional Cheesy Finish
Sprinkle shredded mozzarella or Parmesan over the top. Cover the skillet for a few minutes or broil briefly to melt the cheese for a gooey, irresistible finish.
Serving and Storing Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta
This pasta is best served hot, straight from the skillet, with a sprinkle of fresh parsley for a burst of color. The creamy texture and spiced flavor make it irresistible on its own, but it also pairs well with a variety of side dishes.
Leftovers can be stored in an airtight container in the refrigerator for up to 3 days. When reheating, add a splash of milk or cream to keep the sauce creamy and smooth.
What to Serve With Cheesy Garlic Twisted Pasta?
Garlic Bread
A crunchy, buttery side that perfectly complements the cheesy pasta.
Simple Green Salad
Balances the richness of the pasta with freshness and crunch.
Roasted Vegetables
Carrots, zucchini, and bell peppers roasted with olive oil pair beautifully.
Steamed Broccoli
A healthy and light addition to round out the meal.
Caesar Salad
A creamy, tangy salad option that pairs with the spiced pasta.
Crispy Chicken Tenders
If serving for a crowd, add some crispy chicken for extra protein.
Baked Potato Wedges
Seasoned potato wedges make a hearty and comforting side.
Bruschetta
A fresh tomato and basil topping on crusty bread offers a bright flavor contrast.
Want More Pasta Ideas?
If you love this Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta, you’ll enjoy exploring more flavorful creations on SavorQueen:
• Creamy Velveeta Beef Bowtie Pasta
• Cajun Shrimp with Garlic Butter Sauce
• Garlic Butter Steak Parmesan Rigatoni
• Ultimate One-Pan Creamy Honey Butter Steak Pasta
• Spicy Cajun Steak Mozzarella Alfredo Pasta
Save This Pin For Later
Save this delicious idea to your favorite Pinterest board so it’s easy to find when you’re ready to whip it up again.
Tried it with a twist? Maybe added extra veggies or a dash of hot sauce? Share your version in the comments—we’d love to hear!
Need more inspiration? Explore my daily kitchen creations on SavorQueen Recipes. Your next favorite might be waiting there!

Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta
Equipment
- Large pot
- Large Skillet
- Strainer
Ingredients
Ingredients
- 1 lb rotini pasta
- 1 lb ground beef
- 2 cups Velveeta cheese, cubed
- 2 cups Alfredo sauce
- 2 cloves garlic, minced or 1 tsp garlic powder
- 2 tsp Cajun seasoning
- 1 cup shredded mozzarella or Parmesan (optional)
- 2 tbsp fresh parsley, chopped (optional)
Instructions
- Cook rotini pasta in salted boiling water until al dente. Drain and set aside.
- In a large skillet, brown ground beef over medium heat. Drain excess grease, add Cajun seasoning and garlic, and sauté until fragrant.
- Lower heat, add Alfredo sauce and Velveeta cubes. Stir until smooth and creamy.
- Toss the cooked rotini with the cheesy beef mixture until fully coated.
- Top with shredded cheese and cover or broil for a gooey finish. Garnish with parsley if desired.