This dish is what creamy, savory pasta dreams are made of. Creamy Parmesan Rotini with Cajun Garlic Butter Chicken brings together tender, golden-seared chicken loaded with Cajun spices and a rich, velvety parmesan sauce that clings to every spiral of rotini pasta. It’s a restaurant-style meal you can whip up right in your own kitchen—and trust us, it tastes even better at home.

Perfect for cozy dinners, family meals, or anytime you want to impress without the stress, this pasta is a showstopper. The bold Cajun flavors from the chicken pair perfectly with the creamy parmesan garlic sauce, delivering a spicy, buttery, cheesy experience that keeps everyone coming back for seconds.

What Makes Cajun Chicken Perfect for Creamy Pasta?

The kick of Cajun seasoning cuts through the richness of the cheese sauce, adding balance and depth. The garlic butter finish gives the chicken a caramelized, almost smoky edge that intensifies the overall flavor. Combine that with juicy chicken bites and al dente rotini, and you’ve got a match made in pasta heaven.

Ingredients for the Creamy Parmesan Rotini with Cajun Garlic Butter Chicken

Rotini Pasta – Its twisty shape holds the creamy sauce beautifully in every bite.

Chicken Thighs or Breasts – Juicy and flavorful, they’re seasoned with bold Cajun spices and pan-seared to perfection.

Cajun Seasoning – Brings heat and smokiness that contrast beautifully with the cream sauce.

Garlic & Butter – For that rich, aromatic base that soaks into the chicken.

Heavy Cream – The backbone of the luscious parmesan sauce.

Parmesan Cheese – Nutty and salty, it melts into the cream for a thick, luxurious finish.

Parsley – Fresh and chopped, it adds a bright, herby pop.

Salt & Black Pepper – Balances the heat and rounds out the flavor.

Olive Oil – Used to sear the chicken and build that beautiful golden crust.

How To Make the Creamy Parmesan Rotini with Cajun Garlic Butter Chicken

Step 1: Boil the Pasta

Bring a large pot of salted water to a boil. Cook the rotini until al dente, then drain and set aside. Save 1/2 cup of pasta water.

Step 2: Season and Cook the Chicken

Season chicken generously with Cajun seasoning, salt, and pepper. In a large skillet, heat olive oil over medium-high heat. Sear the chicken until golden and cooked through, about 5–7 minutes per side. Remove and let it rest before slicing.

Step 3: Make the Garlic Butter

In the same skillet, lower the heat and add butter and minced garlic. Stir for 1–2 minutes until fragrant, scraping up brown bits for extra flavor.

Step 4: Create the Creamy Sauce

Pour in heavy cream and simmer. Stir in grated parmesan cheese and reserved pasta water until smooth and thick. Add salt and pepper to taste. Toss in chopped parsley.

Step 5: Combine and Serve

Add cooked rotini into the sauce and stir to coat. Top with sliced Cajun garlic butter chicken. Garnish with more parmesan and parsley if desired.

Serving and Storing This Creamy Rotini Dish

Serve this dish hot for maximum creaminess and flavor. For presentation, pile the pasta onto a large platter and fan out the sliced chicken on top, finishing with a sprinkle of parsley.

Leftovers can be stored in an airtight container in the fridge for up to 3 days. Reheat gently on the stove or microwave with a splash of cream or milk to keep it luscious. Avoid freezing, as the creamy sauce may split.

What to Serve With Creamy Parmesan Rotini with Cajun Garlic Butter Chicken?

Garlic Breadsticks

A crunchy, buttery side that’s perfect for scooping up extra sauce.

Caesar Salad

Crisp lettuce, creamy dressing, and croutons provide refreshing contrast.

Grilled Asparagus

Adds a light, charred vegetable note to balance out the richness.

Roasted Cherry Tomatoes

Bursting with sweetness, they enhance the Cajun seasoning’s depth.

Sautéed Spinach with Garlic

Simple, earthy, and great with the creamy pasta base.

Caprese Skewers

Mini mozzarella, tomato, and basil bites keep things fresh.

Parmesan Zucchini Chips

Light and crispy, these echo the cheesy notes of the dish.

Lemon-Herb Couscous

A zesty, fluffy grain option to add some variety to your table.

Want More Creamy Chicken Pasta Recipes?

If you love creamy Cajun pasta, check out these flavorful dishes:

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Bookmark this Cajun creamy pasta idea on your Pinterest board for those nights when you crave something bold and buttery.

Did you add mushrooms or a twist of lemon zest? Tell us how you made it yours in the comments.

Hungry for more? Dive into my favorite creations on SavorQueen Recipes on Pinterest and discover your next comfort food obsession.

Creamy Parmesan Rotini with Cajun Garlic Butter Chicken

Author: Julia Walton
Total Time: 30 minutes
Yield: 4 servings

Print Recipe

Description

Bring bold flavor to your dinner table with this Creamy Parmesan Rotini with Cajun Garlic Butter Chicken. Juicy Cajun-seasoned chicken bites are seared until golden and tossed over a bed of rotini pasta drenched in a garlicky parmesan cream sauce. It’s comfort food that hits every craving: creamy, spicy, cheesy, and deeply satisfying. This easy recipe is perfect for dinner ideas, quick comfort food, and crowd-pleasing meals that feel like a treat without requiring hours in the kitchen.

Instructions

1. Bring a large pot of salted water to a boil. Cook the rotini until al dente, then drain and set aside. Save 1⁄2 cup of pasta water.

2. Season the chicken with Cajun seasoning, salt, and pepper. Heat olive oil in a skillet over medium-high heat. Sear chicken for 5–7 minutes per side until cooked through. Remove and let rest.

3. In the same skillet, add butter and minced garlic. Sauté for 1–2 minutes until fragrant.

4. Pour in heavy cream and stir in parmesan cheese and reserved pasta water. Simmer until thick and smooth. Season with salt and pepper.

5. Add chopped parsley, then toss in cooked rotini pasta until fully coated in sauce.

6. Slice the chicken and serve on top of the creamy pasta.

7. Garnish with extra parmesan and parsley if desired.