Golden, juicy chicken bites smothered in garlicky butter and a hint of Cajun heat, paired with creamy Alfredo twisted pasta, make this recipe a weeknight hero. Imagine tender chicken cubes seared until slightly crispy, tossed in a velvety garlic butter sauce that fills your kitchen with a mouthwatering aroma.
The Spicy Cajun Alfredo twisted pasta brings a comforting yet bold twist, blending creamy, cheesy notes with a smoky Cajun kick. Each forkful is a perfect harmony of savory chicken and luscious pasta that feels like a restaurant-quality meal, but it’s easy enough for home cooking.
What Kind of Chicken Should I Use?
Boneless, skinless chicken breasts or thighs are ideal for this dish. Breasts offer a leaner option, while thighs provide extra juiciness. Ensure the chicken is cut into small, uniform bites to cook evenly and soak up the buttery, garlicky goodness.


Ingredients for Easy Garlic Butter Chicken Bites with Spicy Cajun Alfredo Twisted Pasta
- Chicken Breasts or Thighs – These are the star of the dish, offering juicy bites that pair perfectly with buttery sauces.
- Butter – Creates that rich and velvety coating on the chicken and pasta.
- Garlic Cloves – Freshly minced for a bold and aromatic flavor.
- Cajun Seasoning – Brings smoky heat and depth to both chicken and sauce.
- Heavy Cream – Forms the creamy base of the Alfredo sauce.
- Parmesan Cheese – Adds a salty, nutty richness to the pasta.
- Twisted Pasta (Rotini or Fusilli) – The spiral shape holds onto every drop of sauce.
- Olive Oil – Helps achieve a golden sear on the chicken bites.
- Parsley – A fresh garnish that brightens the final dish.
How To Make Easy Garlic Butter Chicken Bites with Spicy Cajun Alfredo Twisted Pasta
Step 1: Season and Sear the Chicken
Pat the chicken dry and cut into bite-sized pieces. Toss with Cajun seasoning, salt, and a drizzle of olive oil. Heat a skillet on medium-high and sear the chicken until golden and cooked through.
Step 2: Make the Garlic Butter Base
Lower the heat and add butter and minced garlic to the skillet. Stir until fragrant, letting the chicken absorb the flavors.
Step 3: Prepare the Twisted Pasta
Cook the pasta according to package directions until al dente. Reserve a bit of pasta water for the sauce.
Step 4: Create the Cajun Alfredo Sauce
In the same skillet, pour in heavy cream and a spoonful of pasta water. Whisk in Parmesan cheese and an extra pinch of Cajun seasoning for a creamy, spicy Alfredo.
Step 5: Combine and Serve
Toss the pasta in the sauce, then top with the buttery chicken bites. Sprinkle with fresh parsley and serve hot for a comforting and flavorful dinner.
Serving and Storing Easy Garlic Butter Chicken Bites with Spicy Cajun Alfredo Twisted Pasta
This dish is best served fresh while the pasta is creamy and the chicken is hot. If you need to store leftovers, place them in an airtight container in the refrigerator for up to 3 days. Reheat gently on the stovetop with a splash of milk or cream to restore the sauce’s silky texture.
What to Serve With Easy Garlic Butter Chicken Bites?
1. Garlic Bread
Perfect for soaking up that rich Cajun Alfredo sauce.
2. Caesar Salad
A crisp, creamy side that balances the richness of the pasta.
3. Roasted Vegetables
Broccoli, zucchini, or bell peppers add a healthy, colorful complement.
4. Corn on the Cob
A buttery, sweet side that pairs beautifully with the Cajun spices.
5. Lemon Asparagus
Bright and citrusy, it cuts through the richness of the Alfredo sauce.
6. Caprese Salad
Tomatoes and mozzarella offer a refreshing, tangy contrast.
Want More Chicken Pasta Ideas?
If you love this Easy Garlic Butter Chicken Bites with Spicy Cajun Alfredo Twisted Pasta, you’ll enjoy these delicious SavorQueen creations:
• Cajun Chicken and Sausage Pasta Skillet for a smoky and hearty one-pan meal.
• Garlic Butter Chicken with Rigatoni and Parmesan for a creamy and comforting option.
• Spicy Cajun Steak Mozzarella Alfredo Pasta if you crave an extra kick of spice and cheesy goodness.
• Cheesy Ranch Chicken Garlic Butter Fettuccine for a twist with ranch flavors.
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Easy Garlic Butter Chicken Bites Recipe with Spicy Cajun Alfredo Twisted Pasta
Equipment
- Large Skillet
- Pasta pot
- Strainer
- Wooden spoon
Ingredients
- 1 lb chicken breasts, cut into bite-size pieces
- 2 tbsp olive oil
- 1.5 tbsp Cajun seasoning
- 4 cloves garlic, minced
- 4 tbsp unsalted butter
- 2 cups heavy cream
- 1 cup freshly grated Parmesan cheese
- 12 oz twisted pasta (rotini or fusilli)
- 0.5 tsp salt (adjust to taste)
- 0.25 tsp black pepper
- 2 tbsp chopped fresh parsley
Instructions
- Pat chicken dry, cut into bite-sized pieces, and season with Cajun seasoning.
- Heat olive oil in a skillet over medium-high heat and sear chicken until golden and fully cooked. Remove and set aside.
- In the same skillet, reduce heat to medium and melt butter. Add minced garlic and sauté until fragrant.
- Stir in heavy cream and bring to a gentle simmer. Add Parmesan cheese, salt, black pepper, and a pinch of Cajun seasoning.
- Cook pasta according to package instructions until al dente. Reserve ½ cup pasta water.
- Toss drained pasta into the creamy sauce, adding reserved pasta water as needed to loosen.
- Return chicken to the skillet and stir to coat with sauce.
- Garnish with fresh parsley and serve hot.